Blink Knowledge Base

Introduction:  DNA is a double helical structure (  looks like a ladder )that composed of a pair of nucleotide  base that lie perpendicular to the  parallel double  strand. The nucleotide  bases may be either  a Purine (Adenine 'A' /Guanine 'G') or Pyrimidine  (Thymine 'T' /Cytosine 'C') .  These  nucleotides form the base for gene code and DNA sequence. They varies from organisms  to organisms that makes the individual unique.    SNPs : Sometimes during the process of copying of sequence  from parents  to the progeny a typo error  may occur in a single  nucleotide  sequence  at a particular  position  know as SNP or snips .  It is the single nucleotide  mutation  that occurs  at the specific  position  in the genome  of the individual that causes major variation among the individuals at a frequency  of >1% in the population .  All the ...

Introduction: Government of Tamil Nadu launched UZHAVAN – உழவன் App for farmers in the state. The app provides complete real-time information related to agriculture and also provides 9 important services such as weather updates and latest crop rates. The app is launched by the Chief Minister TN Edappadi K.Palaniswami at the Secretariat. The app supports two languages Tamil and English. UZHAVAN – உழவன் App Benefits: Real-time information such as weather updates & crop prices. Farmers can easily apply for government schemes & subsidies. Track status of their application. Easy application procedure for application of crop insurances. Updates on compensation amount on the insurance and various schemes. Provides information on Customer Hiring Center for hiring farm Machinery. UZHAVAN – உழவன் App Services: Information on farm subsidies. Farmers can book farm equipments. Details about crop insurance and services. Weather forecast for next 6 days. In...

BLAST - Basic Local Alignment  Search Tool   A tool  used to compare the query sequence with database sequence .This tool allows you to take a sequence and search a large database  to find a sequence  that are related to the sequence that you input. This tool have been developed by NCBI . Why this tool is needed? Used to check similarities that exist within and between organisms. Helps in DNA mapping  program.  Used to construct  phylogenetic tree. Helps to infer functional  and evolutionary relationship.  How to use BLAST? First get into the NCBI  website. select the BLAST in the resource option.  There are 5 different  types of blast program. We want to select any one to run your program based on the input sequence. 1. Nucleotide blast   2. Protein blast Both are used based on the input query sequence either a nucleotide or protein sequence. 3. blastx  4. tblastn 5. tblastx These are little bit advanced...

National Center for biotechnology information (NCBI) is a platform which enclose a complete series of data relavant to all biotechnological, biomedical and other bioinformatics services. NCBI is an open public source which could be accessed for free from anywhere in the world. This database have been founded by Claude pepper in 1988 through legislation, whose headquarters is suitated in Betherda Maryland U.S. NCBI is a part of the United States National library of medicine (NLM) , a branch of National Institute of health (NIH).   Entrez is a specially designed search engine mainly used in NCBI which helps in the intergration of all the data from several different sources to the user. How to get information from NCBI In google search Type NCBI and search Go to NCBI page The main 6 basic tools available in NCBI are: Download - this option is mainly used to download all the required genomic information like DNA sequence , protein sequence etc.  through FTP (file transfer protoco...